Devices Clinical Evidence gaps matter & how to close

Finding evidence on a clinical topic is often challenging. The number of medical articles published in MEDLINE increases annually. Searching for the hypodermic needle in the thickening evidence haystack takes time, resources, and considerable skill in devising the right searches.
Why do evidence gaps matter?
Knowing early on in the product development process that there are gaps in the evidence gives manufacturers time to generate the evidence needed to demonstrate the value of their product.
What is evidence gap?
A complete lack of studies on a topic is clearly a gap; but how much information is required to be confident in making a decision?