IVDR Performance Evaluation: ROC in absence of Gold Standard

Gold Standard forms a yardstick in measuring the accuracy of diagnostic tests. In cases of unknown or critical diseases, this gold standard is generally absent and in such situations, the ROC comes into play. The Receiver Operating Characteristic Curve gives the probable output.

A few aspects encircling ROC which has been elaborated in the paper and a brief overview has been given below:

• ROC in the Absence of Gold Standards.
• Area under Curve (AUC).
• Integrated Discrimination Improvement (IDI).
• The functioning of the ROC Curve.